Celebs and their plastic surgery

Jamie Lee Curtis – gender?

Jamie Lee Curtis has decided not to have any more plastic surgery. According to Plasmetic.com she has undergone a lower eyelid surgery and liposuction which led to complications, and has now decided that she will not have anymore. If only she would make the same decision about doing movies with Lindsay Lohan.

In the medical community she is known for a different, not-so-plastic-surgery-related medical condition. Does anyone know what it is?

Photo: prphotos.com


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Wednesday, July 12th, 2006 at 8:19 am | Celebrity Cosmetic Surgery, Jamie Lee Curtis

31 Responses to “Jamie Lee Curtis – gender?”

  1. Anonymous
    Web site:

    July 12th, 2006 at 9:41 am

    So it’s possibly true that she may have been born a hermaphrodite?

  2. Figmo
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    July 12th, 2006 at 11:25 am

    Is there any proof to that rumor? I’ve heard it for years but no one has ever offered up medical records, parent statements, her statments etc. I think she has an interesting beauty.

  3. The_Aitch
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    July 12th, 2006 at 12:45 pm

    Supposable she’s a hermie. I doubt that though.

  4. Anonymous
    Web site:

    July 12th, 2006 at 11:41 pm

    So were we right about that rumor?

  5. Judit
    Web site: blogger.com/profile/06897247772850232993

    July 13th, 2006 at 1:13 am

    She was always more about the body than the face as far as I can see, and has never been such a great feminine beauty, so as long as she goes to the gym to keep the body up, whatever bits she’s got concealed in her panties won’t bother me. But that rumor *is* very tantalizing.

  6. Anonymous
    Web site:

    July 13th, 2006 at 12:06 pm

    Is it androgen insensitivity syndrome?

  7. Dr. Tony Youn
    Web site: blogger.com/profile/15998068685500761233

    July 13th, 2006 at 7:39 pm

    Thanks for all your answers. Now, I am not an expert in genetics, but it is urban legend that Ms. Curtis is a pseudohermaphrodite. That would mean that she has XY chromosomes but developed female external genitalia. I believe that she does not have a real uterus though, as her vagina ends in a “blind-ended sac.” This is by no means a known fact, but what I remember from med school. Unfortunately, I have long ago tossed out my notes and textbook. If anyone has any other information feel free to post.

  8. Anonymous
    Web site:

    July 14th, 2006 at 11:32 am

    I happened to be eating when I read the bit about the blind-ended sac. Thanks a lot.
    Your receptionist

  9. Breast liposuction Simple
    Web site: blogger.com/profile/03985705198142537731

    July 17th, 2006 at 1:40 am

    I am doing reserach on various ways to reduce fat from over all bodyand alos spot.
    I amsetting up a multilingual website on liposuction

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  10. Anonymous
    Web site:

    July 28th, 2006 at 7:03 pm

    When I was an intern I heard from another resident (who had been on the gyne team looking after Ms Curtis) that she had testicular feminization syndrome

  11. Anonymous
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    July 29th, 2006 at 1:29 pm

    I learned in my reproductive genetics class in college that she has Klinefelter’s syndrome– an XXY. Technically she was born a male but ppl with this syndrome often have underdeveloped genitalia, making it easier to have them genetically reassigned to be a female…

  12. Samara
    Web site: blogger.com/profile/17401027077752973943

    August 3rd, 2006 at 1:35 am

    Yep, she’d XXY. Her urologist and my dad (also a urologist) are pals.

  13. Anonymous
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    August 26th, 2006 at 2:41 pm

    i heard she has androgen insensitivity syndrome as well.. rather than klinefelter…

  14. Anonymous
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    November 26th, 2006 at 9:00 pm

    From what I have learned in my college biology class, she has testicular feminization and not kleinfelters. Since her testosterone receptors don’t function properly and her estrogen receptors do, she is essentially female while having XY chromosomes.

  15. Anonymous
    Web site:

    March 5th, 2007 at 5:05 pm

    I studied this in med school, so maybe i can help explain this a bit better… Its a pretty complicated condition, so I can see how it can be confusing to some.

    She can’t have klienfelters (XXY) because people of this genetic disease are pretty much normal males with male external genetalia, testicular atrophy (shrunken testicles) and gynecomastia (boobs).

    She most likely has Androgen insensitivity. In this disorder the person is genetically male like Dr. Youn said with a blind ending vagina (the outer vagina develops independently from the hormone problems here).

    The problem here is a complete LACK of androgen receptor function, thus their bodies do not respond to the high levels of androgens. thus they do not have the internal male structures.

    They do however have testes (internal) and their testosterone levels are normal male levels.

    Since they have what appears to be a vagina (externally), these patients are physiologically and physically female and are brought up as girls. The diagnosis is usually made at puberty when they cannot menstruate due to having NO uterus, fallopian tubes, cervix or UPPer vagina!!! After it is diagnosed, they need estrogen replacement and should have the internal testes removed, because they are at an increased risk of developing Testicular cancer!

    Pretty interesting stuff, huh? :)

  16. Anonymous
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    May 10th, 2007 at 2:18 am

    The post above is what I learnt in med school too. One modification: most androgen insensitivity/testicular feminization sufferers don’t need estrogen therapy since the enzyme that converts testosterone to estradiol (5 alpha reductase) is working normally.

    Although they tend to have higher testosterone levels (the loss of the receptors also inhibits negative feedback) they convert most of it to estradiol, which is why they develop female sexual characteristics normally and on time. In fact, it is usually only at puberty that the syndrome is detected – due to the failure to menstruate. Since hair growth on the pubis, under the arms and on the face is testosterone-dependant, they do not have hair in these places.

  17. Anonymous
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    June 18th, 2007 at 6:31 am

    My bro told me she had Androgen insensitivity. The Shah of Iran’s wife had it as well.

    Furthermore, he said that those with Androgen insensitivity frequently appear ultra-feminine in appearance.

  18. Joni Stehlik
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    August 19th, 2007 at 2:43 pm

    As a geneticist I hope I can explain in layman terms how she became a pseudohermaphrodite. This occurred bc she was born with one X and one Y chromosome (X is the female chromosome and Y is the male chromosome). Most women are born with two X chromosomes and most males are born with one X and one Y. One of the X chromosomes is randomly inactivated in each cell in females, this is called the Lyon Hypothesis (http://en.wikipedia.org/wiki/X-inactivation). Therefore, to be a normal looking female you theoretically need only one active X chromosome. The Y chromosome is very small in comparison and only contains a few genes. Most of these genes on the Y chromosome serve to determine sex (one of these is the SRY gene) http://en.wikipedia.org/wiki/Sex-determination_system. For humans an embryo possessing the lack of a physical and/or functioning Y chromosome will by default become female. In the case of Jamie Lee Curtis, she has both and X and a Y chromosome. Her Y chromosome does not possess a functioning SRY gene.

  19. Anonymous
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    October 6th, 2007 at 12:53 pm

    Jamie Lee Curtis XXY : Urban Legend
    “Without a doubt, the main driving force behind this gossip is the fact that Jamie Lee Curtis’s alleged intersexuality has long been spoken of as a given in medical school classrooms, even though her name has never appeared in a textbook or journal article in connection with intersex conditions. But a rumor is still a rumor, even from the lips of a board-certified physician. All the more so, in fact, given that any physician who actually treated Curtis couldn’t have revealed such information without violating patient confidentiality laws.

    The only document that has ever been offered as “proof” was a 1996 op-ed piece in the Baltimore Sun written by William O. Beeman, associate professor of anthropology at Brown University, entitled “What Are You: Male, Merm, Herm, Ferm or Female?” The relevant passage reads as follows:

    As a result, there are perhaps millions of XX males and XY females living in the United States today. These are cultural males with male genitalia who are genetically female, and cultural females with female genitalia who are genetically male. The film star Jamie Lee Curtis is one well-known individual who is genetically male, but phenotypically female.

    And there we have it in black and white, it would seem, except for two tiny caveats. First, according to Professor Beeman the pertinent sentence was deleted from the published article. Second, the reason it was deleted was that Beeman’s attempts to track down the plastic surgeons to whom intermediate sources had attributed the statement were “totally unsuccessful.” In other words, Professor Beeman had simply repeated an item of scurrilous gossip”

  20. Rusty
    Web site: blogger.com/profile/04165753859756718300

    March 2nd, 2008 at 12:23 am

    AIS results in underdeveloped testicles where her ovaries should be, which secrete testosterone but she lacks receptors to it which results in a default female pathway, in which she has a normal vagina.

    You might recall a house episode about this condition.

    this is not ‘hermaphroditism’, as she is sterile, and does not have ambiguous genitalia at all. Many people live normal lives with this condition, as long as what parts of society learn of it do not hold irrational prejudices against them.

  21. Anonymous
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    September 9th, 2008 at 11:27 am

    Apart from phenotypes and genitalia, how do these patients feel? Do they feel more female if they happen to be raised so?

  22. jedcatch33
    Web site: openid.aol.com/jedcatch33

    October 22nd, 2008 at 10:20 pm

    born with a dick or not, you have to admit he/she was sexy during the strip scene in the movie True Lies!!!

  23. Anonymous
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    November 21st, 2008 at 3:55 pm

    I am genuinely surprised that Dr. Youn would post this rumor without documentation. I appreciate general plastic surgery snarkiness, but this condition seems a bit too personal to read about. She’s one of my favorite celebrities– this rumor probably started because she has always sported a short haircut. Simple as that.

  24. Anonymous
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    December 9th, 2008 at 7:37 pm

    Jamie Lee Curtis is not a hermaphrodite. She has an extra Y chromosome which means androgen insensitivity. Totally different

  25. Anonymous
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    April 10th, 2009 at 7:19 pm

    None of you have any idea about JLC’s genetic and genital status. Christopher Guest would know more.

    These are just rumors. When I was in medical school, my OBGYN resident told me that he personally knew an ER MD who pulled a gerbil out of Richard Gere’s ass. Problem is, that doctor was in NYC, and another resident “knew” a doctor who allegedly degerbiled Gere in LA.

    Lesson: rumors about stars are bogus, even if our residents or attendings repeat them.

  26. Anonymous
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    June 27th, 2009 at 3:05 pm

    I also learned in Med school that she had androgen insensitivity syndrome. However, in a broad search I cannot find any facts to substantiate or even support this claim. For sure she clearly does not have Klinefelter's (XXY) as these are ALL phenotypically male. If she did have Androgen insensitivity (XY), outwardly, she would be totally female, minus periods and the top of her vagina. No hormones would be required, ever, not even after menopause (due to the action of aromatase though, not 5 a- reductase which makes DHT from testosterone). I see no reason to believe at the moment that she has any genetic anomaly.

  27. Hermy Frodite
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    November 5th, 2009 at 2:14 am

    You're all full of crap.

  28. Anonymous
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    March 28th, 2010 at 2:33 pm

    The really retarded thing about the Jamie Lee Curtis rumor is that it undoubtedly arises from the fact she looks so much like her father. The implication being that people think she looks mannish. But people with AIS look very feminine since they can't respond to testosterone. So you would never peg someone with AIS as having AIS in the first place.

    The ironic part is I just ran across another message board where someone said Curtis now sports a mustache. She shouldn't be able to grow one at all if she has AIS, you know.

    If society didn't look down on women who didn't shave, this rumor could have been put to rest ages ago, because she'd have hair in her pits.

  29. Joe
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    December 22nd, 2010 at 10:08 am

    She does NOT have XXY syndrome (AKA Kleinfelter syndrome). Hermaphroditism is a possibility, but unlikely as these people often have shared male and female external appearances. Ms. Curtis is no doubt a female externally, and her female stunning looks are simply not the product of hermaphroditism or intersexuality.
    However, it is possible that she has androgen/testosterone insensitivity syndrome. These people are genetically male (XY) but lack the receptor for testosterone. They have testicles (because they are genetically male) that are undescended and intraabdominally. They have to uterus, cervix or ovaries because internal genitalia develop based off of genetic male or female. However, external genitalia develops strictly based off of sex hormone exposure in utero. If they are exposed (and sensitive) to female hormones, they develop a vagina. If they are exposed to and sensitive to male hormones, they develop a penis and scrotum. People with androgen/testosterone insensitivity are genetically male (hence the male internal organs) but have no receptor for testosterone, so they never develop externally as a male. Everyone is “female” by default in terms of external genitalia until the testes make testosterone, if they ever develop. But, if you don’t respond to it, you simply continue to develop female external genitalia. These individuals typically do not get diagnosed as being testosterone insensitive until 12 or 13 when they go to the doctor for failure to menstruate. They have a shallow vagina that ends as a blind tube (no cervix). They tend to be slender, lean, and have larger breasts. Overall, they tend to have a stunning female appearance.
    I was told she was testosterone insensitive by a professor in medical school. However, the professsor was basing this off of the fact that she had an ambiguous name, never conceived children, and fit the body habitus. This has never been substantiated, but it is possible she does have this syndrome. The only people who know are her, her parents and her doctors.
    She is definitely NOT a hermaphrodite, though.

  30. kami
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    March 2nd, 2011 at 7:52 pm

    This is a very rare case.Patients with this diagnosis Androgen Insensitivity Syndrome normally born as a male however the female characteristics is present as they are beautiful and most are tall. These patients have no womb or ovaries, fallopian tube. The hormone estrogen is given to these patients in the form of pill to enhance the breast and also to develop pubic hairs. No Menstruation occurs during these patients life time..

  31. kami
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    March 2nd, 2011 at 7:54 pm

    This is certainly not a hermaphrodite case . NOT HERMAPHRODITE

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